Carprofen (brand names: Rimadyl, Novox) is a prescription non-steroidal anti-inflammatory drug (NSAID) for dogs. It helps relieve pain and reduce inflammation.
Top uses your team will hear about: long-term management of osteoarthritis (arthritis) pain and short-term control of pain after surgery (soft-tissue or orthopedic). It is for dogs only and is Rx-only.
Urgent red flags to relay to a veterinarian right away: vomiting or diarrhea (especially black/tarry stool or blood), not eating, marked lethargy, yellow gums/eyes, or increased thirst/urination. Your veterinarian can discuss why it was prescribed for this pet and what to watch for based on their history.
Front desk script: Carprofen—also called Rimadyl or Novox—is a prescription anti-inflammatory pain medication for dogs. It’s commonly used for arthritis pain and for pain control after surgery. If you see vomiting, black or bloody stools, not eating, yellow gums/eyes, or big changes in thirst or urination, please call us immediately; if severe, use the nearest emergency hospital. Your veterinarian can review how this medication fits your dog’s specific plan and any monitoring they recommend.
Quick owner FAQs about carprofen (Rimadyl, Novox) for dogs:
Q: What is carprofen and why was it prescribed? A: It’s a prescription NSAID used to reduce pain and inflammation from arthritis or surgery in dogs. Many dogs seem more comfortable within a few days, but timing and duration vary—your veterinarian will advise for your pet.
Q: What side effects should I watch for? A: Call us the same day if you see vomiting, diarrhea, not eating, black/tarry or bloody stools, big behavior changes or lethargy, yellow gums/eyes, or changes in drinking or urination. If there’s collapse, seizures, or vomiting/pooping blood, go to an emergency clinic now. Your veterinarian can discuss monitoring and when bloodwork is recommended.
Q: Can I give carprofen with other medications? A: Do not combine it with other anti‑inflammatories (NSAIDs) or steroids unless your veterinarian specifically directs it. Always tell us about all meds and supplements your dog takes; your veterinarian can confirm what’s safe to use together.
Q: Should I give it with food? A: Carprofen may be given with or without food. If stomach upset occurs, call us before the next dose so the veterinarian can advise.
Q: What if I miss a dose or my dog ate extra chewables? A: Don’t give an extra or double dose without veterinary direction. Chewables are palatable—if you suspect an overdose, contact us or a pet poison control service right away. Keep all meds locked away from pets and children. Your veterinarian can provide the official Client Information Sheet and answer any other questions.
Front desk script: Carprofen is a prescription anti‑inflammatory for dogs that helps with arthritis or post‑surgery pain; many dogs feel better within a few days. Please watch for vomiting, diarrhea, not eating, black or bloody stools, yellow gums/eyes, or big changes in drinking or behavior—call us the same day; if there’s collapse, seizures, or blood in vomit or stool, head to the nearest ER now. Don’t give other pain meds or steroids with carprofen unless the doctor says so, and call us if a dose was missed or if your dog may have eaten extra tablets. We can send you the official FDA client information sheet and have the veterinarian review any specific concerns.
What owners most often report after starting carprofen: upset stomach (vomiting, diarrhea or soft stool), not wanting to eat, and acting less active/tired. These are known NSAID effects. Treat these as not “normal”—the clinic should be notified the same day so the veterinarian can advise next steps. Tell the veterinarian about any other medicines or supplements the dog is getting, as NSAIDs have important safety considerations if combined with other drugs.
Urgent red flags that require immediate care: black, tarry, or bloody stool; vomit with blood or that looks like coffee grounds; yellow gums/eyes/skin (jaundice); very pale gums; severe lethargy/collapse; facial swelling or hives; incoordination, stumbling, or seizures; repeated vomiting; or a marked change in drinking/urination with not eating. Serious reactions can occur without warning, so escalate promptly. Your veterinarian can discuss whether monitoring (like periodic labs) is needed while on carprofen and how to proceed based on the dog’s signs.
Front desk script: Thanks for calling—some dogs on carprofen can have stomach upset, less appetite, or seem low-energy. Those aren’t expected, so I’ll alert our veterinarian to review this today. If you’re seeing black or bloody stool, vomiting blood, yellow gums or eyes, very pale gums, collapse, seizures, facial swelling, or repeated vomiting, please go to the nearest emergency hospital now. I’ll note any other medications or supplements your dog is getting so the doctor has the full picture.
Forms and how to give: Carprofen for dogs is dispensed as chewable tablets and caplets for home use; your veterinarian may also give an injection in-clinic. Chewables are very palatable—offer by hand or place on a small amount of food, and watch to be sure the full dose is eaten. Tablets are scored to split if the veterinarian instructs. Store securely out of your dog’s reach; dogs may eat large amounts if they find the bottle. Do not combine with other pain relievers (other NSAIDs) or steroids unless the veterinarian specifically directs.
Pilling tips: Hide the tablet in a small “meatball” of canned food, cheese, or a pill pocket; or coat with a small amount of peanut butter—confirm the product is xylitol‑free (xylitol is toxic to dogs). If your dog still refuses, your veterinarian can discuss switching between caplets/chewables or using a flavored compounded form from a licensed pharmacy when medically appropriate; note that compounded products are not FDA‑approved.
Troubleshooting stomach upset: If a dog vomits after a dose or seems off food, giving with a small meal next time may help. If vomiting persists, or you see black/tarry stool, blood in vomit or stool, yellow gums/eyes, marked lethargy, collapse, or seizures, seek immediate veterinary care. For any vomiting after a dose, contact the veterinarian before giving more so they can advise next steps.
Front desk script: Carprofen comes as chewable tablets and caplets; most dogs will take the chewable by hand or in a small bite of food—please watch to be sure the whole piece is eaten. If your dog won’t take it, I can have our veterinarian discuss other options, including a flavored compounded liquid. If your dog vomits after a dose, please call us before giving more; and if you see black or bloody stool, vomit with blood, yellow gums or eyes, or your dog seems very weak, go to the nearest emergency clinic now.
Carprofen is an Rx-only NSAID for dogs. For any refill request, confirm the pet’s name, owner, medication name/form, how many doses are left, preferred pickup vs. pharmacy, and contact info. Check the chart for: prescription expiration/refills remaining, last doctor exam, and any notes about needed blood or urine testing. Because long-term NSAID use requires monitoring, the veterinarian may require a check-up and/or lab work before approving more medication. Provide the FDA Client Information Sheet with each refill and route any medical questions to the veterinarian.
Red flags while a dog is on an NSAID include vomiting, diarrhea, black or bloody stools, not eating, low energy, or yellow gums/eyes. If any of these are reported, stop the routine refill workflow and escalate to a veterinarian or licensed technician for same-day guidance. If the caller mentions the dog is also taking another pain reliever (another NSAID) or a steroid such as prednisone, flag and route to the veterinarian before proceeding. For online pharmacy requests, only process to licensed pharmacies that require a valid prescription and that will contact our hospital for verification; sites that don’t require a prescription are a red flag. Your veterinarian can discuss whether a recheck or lab work is needed and the safest plan for ongoing therapy.
Front desk script: Thanks for calling about a carprofen refill for [Pet]. I’ll verify the prescription on file, confirm the last exam and any monitoring that may be due, and send your request to the veterinarian; standard turnaround is up to two business days. If [Pet] has vomiting, diarrhea, black stools, isn’t eating, seems unusually tired, or you notice yellow gums or eyes, please tell me now so I can connect you with the medical team today. Do you prefer to pick up here, or should we send the approved prescription to a licensed online pharmacy? Legitimate pharmacies will request our authorization.
Escalate to a veterinarian or technician immediately if a dog on carprofen shows any of the following: vomiting (especially with blood or “coffee‑grounds”), black or tarry stools, repeated diarrhea, not eating, marked lethargy or behavior changes, wobbliness/incoordination, pale gums, yellow gums/skin/eyes, or increased drinking and urination. These can signal serious stomach/intestinal bleeding, kidney problems, or rare liver injury, and reactions can occur without warning. Do not give advice about dosing—get medical staff right away.
If an overdose is suspected (dog chewed the bottle or received more than prescribed), treat as an emergency. Watch for vomiting, diarrhea, bloody vomit, black stools, lethargy, abdominal pain, increased thirst/urination, or seizures. Because carprofen chewables are very palatable, accidental large ingestions are a known risk—immediate veterinary assessment is needed; have the medication bottle available for the medical team.
Escalate urgently for signs of a severe allergic reaction such as facial swelling, hives, or trouble breathing. Your veterinarian can discuss risks, monitoring, and the safest next steps for this patient.
Front desk script: Those symptoms can be serious with carprofen. I’m going to put you through to our medical team right now so they can assess your dog immediately. If your dog chewed the medication or got extra doses, please keep the bottle with you for the vet. If we get disconnected or your dog worsens, please head to the nearest emergency animal hospital right away—our veterinarian can discuss the safest next steps.
Flag and hand off to the veterinarian any time an owner mentions another anti‑inflammatory or steroid with carprofen. Combining carprofen with another NSAID (for example, aspirin, meloxicam, deracoxib, firocoxib) or with a corticosteroid (prednisone, prednisolone, dexamethasone) increases the risk of stomach/intestinal bleeding, ulcers, and kidney or liver problems. Owners sometimes give human OTC products—ibuprofen/Advil, naproxen/Aleve, aspirin, or Pepto‑Bismol (bismuth subsalicylate, a salicylate)—these should be flagged immediately for veterinarian review because they can be dangerous with carprofen. If the owner reports black/tarry stools, blood in vomit, severe vomiting/diarrhea, collapse, seizures, or yellow gums/eyes, direct them to an emergency clinic now and notify the veterinarian at once.
Also flag common interaction categories for veterinarian review: heart/kidney medicines such as ACE inhibitors (enalapril, benazepril) and diuretics (furosemide), blood thinners/anticoagulants, seizure medicines (phenobarbital), immune‑modulating drugs (cyclosporine), insulin, certain antibiotics (e.g., aminoglycosides, sulfonamides), and SSRIs such as fluoxetine. These combinations may require monitoring or an alternate plan—your veterinarian can discuss risks and next steps with the owner.
Meds often mentioned alongside carprofen in multimodal plans include gabapentin or amantadine for pain control, trazodone for anxiety/sedation around visits, anti‑nausea medicine after surgery, and GI protectants like omeprazole or famotidine. These are used only under a veterinarian’s direction. Collect a complete list of all prescriptions, OTC drugs, and supplements and hand off to the veterinarian to confirm safety before the owner gives anything new.
Front desk script: Thanks for telling me about the other medication. Some drugs, including human pain relievers like ibuprofen, naproxen, aspirin, or Pepto‑Bismol, can be dangerous when a dog is on carprofen, so I’m going to have our veterinarian review this right away before you give anything else. If any of those were already given today with carprofen, or if you see black stool, blood in vomit, severe vomiting/diarrhea, collapse, seizures, or yellow gums/eyes, please go to the nearest emergency vet now—I can call ahead for you. Otherwise, I’ll get a same‑day callback from the doctor to go over safe options.
Store carprofen chewable tablets at room temperature. Labels for Rimadyl and generics allow 59–86°F (15–30°C), and some generics specify a preferred 68–77°F (20–25°C) with brief excursions to 59–86°F permitted. Keep the medication in its original, labeled, child‑resistant container and store it out of reach of pets and children. Flavored chewables are attractive to dogs, so secure the bottle in a closed cabinet.
If a pet or child swallows more than prescribed or gets into the bottle, treat this as urgent: contact the veterinarian or a veterinary emergency clinic immediately; for human exposure, contact Poison Control. Your veterinarian can discuss safe storage during travel or in homes with multiple pets.
Shelf life after opening: product labels do not specify a shorter “use by” period for unopened whole tablets once the bottle is opened. However, several carprofen chewable labels instruct that if a tablet is split, the remaining half should be used within 30 days. For disposal, use a take‑back location or FDA mail‑back program when possible. If no take‑back is available and the drug is not on the FDA Flush List, dispose of it in household trash per FDA directions (e.g., mix with an unappealing substance, seal, then discard). Your veterinarian can advise on clinic or community disposal options.
Before a dog starts carprofen, schedule a doctor exam and baseline lab work (blood ± urine) so the veterinarian has starting values for liver and kidney health. A first recheck with an exam and bloodwork is typically set 2–4 weeks after starting or after any dose change to make sure the medication is being tolerated; your veterinarian can adjust timing based on the pet’s risk factors and history. FDA labeling also asks that owners receive the NSAID Client Information Sheet and that pets on NSAIDs have periodic follow‑ups while on treatment.
For ongoing therapy, plan periodic monitoring to check liver and kidney values and assess comfort. Many patients are rechecked every 6–12 months when stable; seniors or pets with other health concerns may be seen more often as directed by the veterinarian. If an owner reports red-flag signs such as not eating, vomiting or diarrhea, black/tarry stools, yellow gums/eyes, marked lethargy, seizures, or big changes in drinking or urination, escalate to a veterinarian the same day for guidance on next steps.
Front desk script: For carprofen, we’ll book a recheck with bloodwork about 2–4 weeks after starting, then periodic monitoring visits to check liver and kidney function. After that, many dogs are seen every 6–12 months, but the doctor will set the exact schedule for your pet. If you notice vomiting, black stools, not eating, yellow gums/eyes, seizures, or big changes in drinking or urination, please call us right away so the veterinarian can advise you; if it’s after hours, go to the emergency clinic. We’ll also provide the FDA Client Information Sheet so you know what to watch for at home.
Carprofen is a prescription nonsteroidal anti-inflammatory drug (NSAID) for dogs used to reduce pain and inflammation from osteoarthritis and to control postoperative pain after soft‑tissue or orthopedic surgery. It is marketed under several brand names, including Rimadyl and Novox, and is for dogs only.
Common side effects owners may report include vomiting, diarrhea, decreased appetite, or lower energy. Urgent red flags that require immediate escalation include black or tarry stools, bloody vomit, yellow gums/eyes, severe lethargy or collapse, pale gums, incoordination, or seizures. Increased thirst or urination can also be concerning and should be relayed to the veterinarian the same day.
Front‑office safety notes: confirm all current medications—especially other NSAIDs or steroids—since these are typically not used together unless directed by the veterinarian. Rimadyl/carprofen chewables are very palatable; if a dog gets into the bottle or eats extra tablets, treat as an emergency and direct the client to an emergency hospital or pet poison control while we alert the veterinarian.
Front desk script: Thank you for calling [Hospital Name], this is [Your Name]—I’m happy to help with your dog’s carprofen. It’s a prescription pain and anti‑inflammatory medication for dogs; some dogs can have mild stomach upset—our veterinarian can review what’s expected and what to watch for. If you’re seeing repeated vomiting, black or tarry stools, yellow gums/eyes, collapse, or your dog ate extra tablets, please go to the nearest emergency vet now. I can’t advise on dosing, starting/stopping, or combining this with other meds over the phone—let me have our veterinarian review your pet’s record; may I place you on a brief hold or arrange a same‑day call back? If there are no urgent signs, I can also request a refill or schedule an appointment—what’s the best number and time for today?